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PodcastSmart Biotech Scientist | The CMC and Bioprocessing Podcast for Process Development and Manufacturing LeadersOctober 22, 2026

298: 10,000 Structures Are Not Enough: The Data Gap Limiting De Novo Antibody Design with David Younger - Part 2

A-Alpha Bio's new data consortium aims to multiply public antibody affinity data 200x+ by pooling prospective, pre-competitive experiments across pharma and AI labs.

  • Data consortium launched: A-Alpha Bio's five founding members each receive ~28M affinity measurements/year, versus only ~500,000 total antibody affinity measurements publicly available today.
  • A-Alpha Bio dominates public data: Younger estimates upwards of 75% of all public antibody affinity data originates from his company's own AlphaSeq publications.

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