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PodcastThe a16z ShowOctober 20, 2026

What Happens When Everyone Has a Health Expert in Their Pocket? | OpenAI’s Karan Singhal

OpenAI is betting that training medical expertise into general frontier models, not standalone ones, will make health intelligence both better and dramatically cheaper.

  • 300M weekly health users: OpenAI reports over 300 million people use ChatGPT weekly for health/wellness questions, mostly free-tier users, majority outside the U.S.
  • Trained-in, not bolt-on: Singhal says OpenAI embeds specialized healthcare data into every training stage of its general frontier models rather than building separate medical models, which he argues would quickly fall behind the frontier.

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