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PodcastNo PriorsOctober 15, 2026

Revolutionizing Cybersecurity and AI-Driven Science with OpenAI President Greg Brockman

Brockman argues AI has crossed into generating new knowledge and that security spend should structurally exceed software spend as AI reshapes cyber risk.

  • Math milestone claimed: Brockman says OpenAI's AI agents have resolved nearly 400 open, century-old math problems, calling it proof AI can generate genuinely new knowledge.
  • Drug discovery as priority: Brockman ranks biology/drug discovery as the top application to revolutionize, citing the $1.5B/15-year pipeline (~$50M preclinical, ~$1.4B clinical) and biology's data bottleneck versus math's abundant data.

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