Best Tools for Gut Health & Weight Loss | Dr. Chris Thompson

GLP-1 drug adherence is poor (50% quit within a year), driving development of targeted endoscopic procedures and gene therapy alternatives.

• Fiber and microbiome: WHO/Lancet data show most Western populations under-consume fiber (target ~35g/day men, 25g women); resistant starch (RS2) at 40g improved fatty liver and insulin sensitivity in trials.
• GLP-1 adherence crisis: Over a million people/month discontinue GLP-1s—30% quit within a month, 50% by year-end—often due to muscle loss, nausea, or needle fatigue; ~85% of Thompson's endoscopic-procedure patients had already tried and struggled with GLP-1s.

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